Article
Bacterial adhesion to target cells enhanced by shear force.
Cell - 28 Jun 2002
Thomas Wendy E, Trintchina Elena, Forero Manu, Vogel Viola, Sokurenko Evgeni V
Abstract excerpt
Surface adhesion of bacteria generally occurs in the presence of shear stress, and the lifetime of receptor bonds is expected to be shortened in the presence of external force. However, by using Escherichia coli expressing the lectin-like adhesin FimH and guinea pig erythrocytes in flow chamber experiments, we show that bacterial attachment to target cells switches from loose to firm upon a 10-fold increase in...
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