Article
The mexR repressor of the mexAB-oprM multidrug efflux operon in Pseudomonas aeruginosa: characterization of mutations compromising activity.
Journal of bacteriology - 1 Aug 2002
Adewoye Lateef, Sutherland Ainsley, Srikumar Ramakrishnan, Poole Keith
Abstract excerpt
Mutations in mexR yield a multidrug resistance phenotype in nalB mutants of Pseudomonas aeruginosa as a result of derepression of the mexAB-oprM multidrug efflux operon. MexR produced by several nalB strains carried single amino acid changes that compromised MexR stability or its ability to dimer...
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