Article
Altered expression and allelic association of the hypervariable membrane mucin MUC1 in Helicobacter pylori gastritis.
Gastroenterology - 1 Jul 2002
Vinall Lynne E, King Marie, Novelli Marco, Green Carole A, Daniels Geoff, Hilkens John, Sarner Martin, Swallow Dallas M
Abstract excerpt
BACKGROUND & AIMS: Infection with Helicobacter pylori causes chronic gastritis, and this confers a risk of gastric cancer. Short alleles of the membrane-bound mucin MUC1, which has a large extracellular highly glycosylated domain and is highly polymorphic due to variation in the number of tandemly repeated (TR) 20-amino acid units, have been shown to be associated with gastric cancer. Our aim was to investigate...
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