Article
Polymorphism and heteroplasmy of mitochondrial DNA in the D-loop region in Taiwanese.
Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Apr 2002
Chen Ming-Houng, Lee Horng-Mo, Tzen Chin-Yuan
Abstract excerpt
BACKGROUND AND PURPOSE: Although the displacement loop (D-loop) of mitochondrial DNA (mtDNA) is known to have a large number of sequence variations, data on this variation are lacking. This study investigated D-loop sequence polymorphism in Taiwanese subjects. METHODS: The D-loop mtDNA region was amplified from whole blood samples of 63 unrelated Taiwanese individuals using the polymerase chain reaction (PCR)....
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