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Article

Sheep mitochondrial heteroplasmy arises from tandem motifs and unspecific PCR amplification.

Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 Jan 2018

E Guang-Xin, Zhao Yong-Ju, Huang Yong-Fu

Abstract excerpt

The mitochondrial DNA control region (D-loop) is a widely used molecular marker in evolutionary and phylogeographic research. However, the occurrence of heteroplasmy of the D-loop region within individuals has rarely been investigated. In this study, a total of 85 Chinese sheep were used to amplify a partial D-loop region, and 15 heteroplasmic animals (17.64%) were identified. A comparative analysis of the PCR...

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Identifiers

PMID: 27841052
DOI: 10.1080/24701394.2016.1242582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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