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Article

The silencer activity of the novel human serotonin transporter linked polymorphic regions.

Neuroscience letters - 12 Jul 2002

Sakai Kazuo, Nakamura Masayuki, Ueno Shu-ichi, Sano Akira, Sakai Norio, Shirai Yasuhito, Saito Naoaki

Abstract excerpt

Enhancer/silencer activity of each allelic variant of the human serotonin transporter linked polymorphic region (5-HTTLPR) including newly found ones was measured in several cell lines including raphe-nucleus-derived RN46A. 5-HTTLR variants ligated in pGL-3 promoter vector increased luciferase activity in COS-7 cells and PC12 cells, where no significant differences among the variants were observed. In RN46 cell...

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Identifiers

PMID: 12098489
DOI: 10.1016/s0304-3940(02)00348-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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