Article
A polymorphism of the norepinephrine transporter gene in bipolar disorder and schizophrenia: lack of association.
Neuropsychobiology - 1 Jan 2002
Leszczyńska-Rodziewicz Anna, Czerski Piotr M, Kapelski Paweł, Godlewski Sebastian, Dmitrzak-Weglarz Monika, Rybakowski Janusz, Hauser Joanna
Abstract excerpt
Norepinephrine is one of the neurotransmitters which has been implicated in the pathogenesis of mood disorders and schizophrenia. The norepinephrine transporter (NET) gene may be a candidate gene for the study of the genetics of these disorders. In this study, 198 patients with schizophrenia and 100 patients with bipolar disorder were analysed for a silent mutation 1287 A/G, located in the coding region (exon 9)...
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