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Article

Amplification of the effects of drug resistance mutations by background polymorphisms in HIV-1 protease from African subtypes.

Biochemistry - 9 Jul 2002

Velazquez-Campoy Adrian, Vega Sonia, Freire Ernesto

Abstract excerpt

The vast majority of HIV-1 infections worldwide are caused by the C and A viral subtypes rather than the B subtype prevalent in the United States and Western Europe. Genomic differences between subtypes give rise to sequence variations in the encoded proteins, including those identified as targets for antiretroviral therapies. In the case of the HIV-1 protease, we reported earlier [Velazquez-Campoy et al. (2001)...

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Identifiers

PMID: 12093278
DOI: 10.1021/bi020160i

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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