Article
A low genomic number of recessive lethals in natural populations of bluefin killifish and zebrafish.
Science (New York, N.Y.) - 28 Jun 2002
McCune Amy R, Fuller Rebecca C, Aquilina Allisan A, Dawley Robert M, Fadool James M, Houle David, Travis Joseph, Kondrashov Alexey S
Abstract excerpt
Despite the importance of selection against deleterious mutations in natural populations, reliable estimates of the genomic numbers of mutant alleles in wild populations are scarce. We found that, in wild-caught bluefin killifish Lucania goodei (Fundulidae) and wild-caught zebrafish Danio rerio (Cyprinidae), the average numbers of recessive lethal alleles per individual are 1.9 (95% confidence limits 1.3 to 2.6)...
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