Article
How many lethal alleles?
Trends in genetics : TIG - 1 Feb 2003
Halligan Daniel L, Keightley Peter D
Abstract excerpt
Knowledge of the frequency of lethal mutant alleles in a population is important for our understanding of population genetics and evolution, and yet there have been few attempts to measure their number in wild populations. A new study has revealed unexpectedly low numbers of segregating lethal alleles in two species of fish. More experiments are needed, however, to know whether this result is general.
Topics
- Alleles
- Animals
- Crosses, Genetic
- Drosophila
- Female
- Fishes
- Genes, Lethal
- Genes, Recessive
- Genetics, Population
- Homozygote
- Humans
- Male
- Models, Genetic