Article
Age-associated cardiomyopathy in heterozygous carrier mice of a pathological mutation of carnitine transporter gene, OCTN2.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jul 2002
Xiaofei E, Wada Yasuhiko, Dakeishi Miwako, Hirasawa Fujiko, Murata Katsuyuki, Masuda Hirotake, Sugiyama Toshihiro, Nikaido Hiroko, Koizumi Akio
Abstract excerpt
The purpose of this study was to test whether heterozygotes of juvenile visceral steatosis mice, a model for systemic carnitine deficiency, may develop age-associated cardiomyopathy. Tissue morphological observations were carried out by light and electron microscopy to compare the heterozygous an...
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