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Article

TIRAP mediates endotoxin-induced NF-kappaB activation and apoptosis in endothelial cells.

Biochemical and biophysical research communications - 5 Jul 2002

Bannerman Douglas D, Erwert Ryan D, Winn Robert K, Harlan John M

Abstract excerpt

Bacterial lipopolysaccharide (LPS) initiates multiple signaling events in vascular endothelial cells that can result in activation and/or cell death. LPS-induced activation of endothelial cells elicits a wide array of vascular endothelial responses, many of which are dependent on NF-kappaB activation. Several of the signaling molecules that mediate LPS-induced NF-kappaB activation, including Tlr-4, MyD88, and...

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Share to Apoptosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Interleukin-1

Source

Identifiers

PMID: 12083783
DOI: 10.1016/s0006-291x(02)00638-1

Genes

TIRAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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