Article
Characterization of an HIV type 1 strain with preferential replication in adherent cells.
AIDS research and human retroviruses - 10 Jun 2002
Serra Caterina, Mameli Giuseppe, Biolchini Adriana, Ziccheddu Maria, Curreli Sabrina, Arru Giannina, Dolei Antonina
Abstract excerpt
HIV-E, emerging from persistently infected HeLa-T4 cells, replicates better in fibroblasts and epithelial cells with respect to the parental, T cell-derived HIV-T. The two viruses share the same env V3 loop, but differ in cellular molecules incorporated on the envelope. Even when similar amounts of virus attachment occurred, HIV-E replicated better than HIV-T in cells from solid tissues, and the response to...
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