Article
Extending the coalescent to multilocus systems: the case of balancing selection.
Genetical research - 1 Apr 2002
Barton Nick H, Navarro Arcadio
Abstract excerpt
Natural populations are structured spatially into local populations and genetically into diverse 'genetic backgrounds' defined by different combinations of selected alleles. If selection maintains genetic backgrounds at constant frequency then neutral diversity is enhanced. By contrast, if background frequencies fluctuate then diversity is reduced. Provided that the population size of each background is large...
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