Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic diversity and evolution of the human leptin locus tetranucleotide repeat.

Human genetics - 1 May 2002

Moffett Susan, Martinson Jeremy, Shriver Mark D, Deka Ranjan, McGarvey Stephen T, Barrantes Ramiro, Ferrell Robert E

Abstract excerpt

To better understand the evolutionary history of the gene region containing the multifunctional adipose tissue hormone leptin, we genotyped 1,957 individuals from 12 world populations for a highly variable tetranucleotide repeat polymorphism located 476 bp 3' of exon 3 of the leptin gene. Common alleles shared among populations, alleles specific to geographically defined populations, and the homologous alleles in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ethnicity
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Leptin

Share to Microsatellite Repeats

Share to Polymorphism, Genetic

Share to Primates

Share to Racial Groups

Source

Identifiers

PMID: 12073010
DOI: 10.1007/s00439-002-0715-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic diversity and evolution of the human leptin locus tetranucleotide repeat.PMID 12073010Read ↗

Triplet repeat length bias and variation in the human transcriptome.Semantic proximity Read ↗

Tandem repeat variation in human and great ape populations and its impact on gene expression divergenceSemantic proximity Read ↗

Tandem repeat variation in human and great ape populations and its impact on gene expression divergence.Semantic proximity Read ↗

Exonic and Intronic Sequence Variation in the Human Leptin Receptor Gene (LEPR)Semantic proximity Read ↗

Dispersion and insertion polymorphism in two small subfamilies of recently amplified human Alu repeats.Semantic proximity Read ↗

Short tandem repeat polymorphism evolution in humans.Semantic proximity Read ↗

Evolution of a hypervariable region of the low density lipoprotein receptor (LDLR) gene in humans and other hominoids.Semantic proximity Read ↗

Single nucleotide polymorphisms and recombination rate in humans.Semantic proximity Read ↗

Determination of ancestral alleles for human single-nucleotide polymorphisms using high-density oligonucleotide arrays.Semantic proximity Read ↗

DNA sequences of Alu elements indicate a recent replacement of the human autosomal genetic complement.Semantic proximity Read ↗

Sequence polymorphism at the human apolipoprotein AII gene ( APOA2): unexpected deficit of variation in an African-American sample.Semantic proximity Read ↗

Different selective pressures shape the molecular evolution of color vision in chimpanzee and human populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.