Article
Influence of cytokine gene polymorphisms on the development of prostate cancer.
Cancer research - 15 Jun 2002
McCarron Sarah L, Edwards Stephen, Evans Philip R, Gibbs Roz, Dearnaley David P, Dowe Anna, Southgate Christine, Easton Douglas F, Eeles Rosalind A, Howell W Martin
Abstract excerpt
Polymorphisms in the promoter regions of cytokine genes may influence prostate cancer (PC) development via regulation of the antitumor immune response and/or pathways of tumor angiogenesis. PC patients (247) and 263 controls were genotyped for interleukin (IL)-1beta-511, IL-8-251, IL-10-1082, tumor necrosis factor-alpha-308, and vascular endothelial growth factor (VEGF)-1154 single nucleotide polymorphisms....
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