Article
Localization, genomic organization, and alternative transcription of a novel human SAM-dependent methyltransferase gene on chromosome 2p22-->p21.
Cytogenetics and cell genetics - 1 Jan 2001
Zhang Y, Gorry M C, Hart P S, Pettenati M J, Wang L, Marks J J, Lu X, Hart T C
Abstract excerpt
As part of our studies to identify the gene responsible for hereditary gingival fibromatosis, GINGF (OMIM 135300), we have identified and cloned a novel human gene that contains the highly conserved methyltransferase domain characteristic of S-adenosylmethionine-dependent methyltransferases. We localized this gene (C2orf8 encoding 288L6 SAM-methyltransferase) to chromosome 2p22-->p21 by FISH, and sublocalized it...
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