Article
Genetic diversity of three lgt loci for biosynthesis of lipooligosaccharide (LOS) in Neisseria species.
Microbiology (Reading, England) - 1 Jun 2002
Zhu Peixuan, Klutch Michael J, Bash Margaret C, Tsang Raymond S W, Ng Lai-King, Tsai Chao-Ming
Abstract excerpt
Lipooligosaccharide (LOS) is a major virulence factor of the pathogenic Neisseria. Nine lgt genes at three chromosomal loci (lgt-1, 2, 3) encoding the glycosyltransferases responsible for the biosynthesis of LOS oligosaccharide chains were examined in 26 Neisseria meningitidis, 51 Neisseria gonorrhoeae and 18 commensal Neisseria strains. DNA hybridization, PCR and nucleotide sequence data were compared to...
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