Article
Genetic polymorphisms: importance for response to HMG-CoA reductase inhibitors.
Atherosclerosis - 1 Aug 2002
Maitland-van der Zee Anke Hilse, Klungel Olaf H, Stricker Bruno H Ch, Monique Verschuren W M, Kastelein John J P, Leufkens Hubertus G M, de Boer Anthonius
Abstract excerpt
Coronary artery disease is among the leading causes of death worldwide. Clinical trials show a protective effect of statins against the sequelae of coronary artery disease. The mean risk reductions for subjects using statins compared with placebo found in these trials is about 30%. These are average reductions for all patients included in the trials. Important factors in interpreting the variability in the...
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