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Article

HER2 Assessment by Immunohistochemical Analysis and Fluorescence In Situ Hybridization

1 Jun 2002

Abstract excerpt

We determined HER2 protein overexpression by immunohistochemical analysis and HER2 gene amplification by fluorescence in situ hybridization (FISH) in 215 formalin-fixed, paraffin-embedded breast tumors. Pathologist concordance for immunohistochemical scoring, and HER2 status concordance, as determined by immunohistochemistry and FISH, were high for immunohistochemical 3+, 1+, and 0 tumors but poor for 2+ tumors....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 12047146
DOI: 10.1309/3643-f955-7q6b-ewwl

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