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Article

[Clinical characteristics of a family with early-onset Alzheimer's disease associated with a presenilin 1 mutation (M139T)].

Medicina clinica - 18 May 2002

Lleó Alberto, Blesa Rafael, Gendre Jordi, Castellví Magda, Molinuevo José Luis, Oliva Rafael

Abstract excerpt

BACKGROUND: The objective of this study was to describe the clinical features and the genetic analysis of a family with autosomal-dominant familial Alzheimer's disease. PATIENTS AND METHOD: In addition to the clinical findings of different family members, we performed a genetic analysis to detect mutations in the amyloid precursor protein genes, presenilin 1 and presenilin 2 genes, by means of single-strand...

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Source

Identifiers

PMID: 12042135
DOI: 10.1016/s0025-7753(02)72501-3

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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