Article
Prevalence and genetic characterization of toxin A variant strains of Clostridium difficile among adults and children with diarrhea in France.
Journal of clinical microbiology - 1 Jun 2002
Barbut Frédéric, Lalande Valérie, Burghoffer Béatrice, Thien Huong Vu, Grimprel Emmanuel, Petit Jean-Claude
Abstract excerpt
Toxin A variant strains (toxin A-negative, toxin B-positive strains) of Clostridium difficile have been reported to be responsible for diarrhea or pseudomembranous colitis in humans. These strains lack parts of the repeating sequences of the toxin A gene (tcdA) and are toxin A negative by commercial enzyme immunoassays (EIA). Here, we report the prevalence of the toxin A variant strains in 334 patients with C....
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