Article
Angiotensin-converting enzyme I/D polymorphism and hypertension: the Ohasama study.
Journal of hypertension - 1 Jun 2002
Matsubara Mitsunobu, Suzuki Michiko, Fujiwara Tohru, Kikuya Masahiro, Metoki Hirohito, Michimata Mari, Araki Tsutomu, Kazama Itsuro, Satoh Tomomi, Hashimoto Junichiro, Hozawa Atsushi, Ohkubo Takayoshi, Tsuji Ichiro, Katsuya Tomohiro, Higaki Jitsuo, Ogihara Toshio, Satoh Hiroshi, Imai Yutaka
Abstract excerpt
OBJECTIVE: Angiotensin-converting enzyme (ACE) I/D polymorphism in intron 16 of the ACE gene was analyzed in a general Japanese population in relation to self-blood pressure (BP) measurement at home (home BP) and ambulatory BP monitoring (ABPM) to determine the association between genetic variants of this polymorphism and hypertension. DESIGN: A cross-sectional study. METHODS AND RESULTS: We genotyped the ACE I/D...
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