Article
Relationship of clinical and virological factors with hepatitis activity in hepatitis B e antigen-negative chronic hepatitis B virus-infected patients.
Journal of viral hepatitis - 1 May 2002
Sung Joseph J-Y, Chan H L-Y, Wong M L, Tse C-H, Yuen S C-H, Tam J S-L, Leung N W-Y
Abstract excerpt
To investigate the factors associated with active disease among hepatitis B surface antigen (HBsAg) positive/hepatitis B e antigen (HBeAg)-negative chronic hepatitis B virus (HBV) infection we studied chronic HBV infected patients who had undetectable HBeAg at the first visit. HBV DNA was determined by the cross-linking assay (NAXCOR) and polymerase chain reaction (PCR). Mutations in the core promoter and precore...
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