Article
Is it necessary to delay antiviral therapy for 3-6 months to anticipate HBeAg seroconversion in patients with HBeAg-positive chronic hepatitis B in endemic areas of HBV genotype C?
Clinical and molecular hepatology - 1 Dec 2014
Song Byung-Cheol, Cho Yoo-Kyung, Jwa Hyeyoung, Choi Eun Kwang, Kim Heung Up, Song Hyun Joo, Na Soo-Young, Boo Sun-Jin, Jeong Seung Uk
Abstract excerpt
BACKGROUND/AIMS: Spontaneous HBeAg seroconversion occurs frequently in the immune reactive phase in HBeAg-positive chronic hepatitis B (CHB). Therefore, observation for 3-6 months before commencing antiviral therapy is recommended in patients with alanine aminotransferase (ALT) levels that exceed twice the upper limit of normal (ULN). However, HBeAg seroconversion occurs infrequently in patients infected with...
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