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Article

Pulmonary pathologies in pallid mice result from nonhematopoietic defects.

Experimental and molecular pathology - 1 Jun 2002

McGarry Michael P, Borchers Michael, Novak Edward K, Lee Nancy A, Ohtake Patricia J, Lee James J, Swank Richard T

Abstract excerpt

Several single gene pigment mutants of inbred C57BL/6J mice display a triad of subcellular granule-associated defects: oculocutaneous pigment dilution, prolonged bleeding due to defects in platelet dense granules, and abnormal lysosomes. These features also characterize Hermansky-Pudlak Syndrome (HPS), making these mice relevant animal models for HPS. Mice of one mutant strain, pallid, in addition to the hallmark...

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Source

Identifiers

PMID: 12009785
DOI: 10.1006/exmp.2002.2431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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