The murine pallid mutation is a platelet storage pool disease associated with the protein 4.2 (pallidin) gene.

doi:10.1038/ng0992-80

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Article

The murine pallid mutation is a platelet storage pool disease associated with the protein 4.2 (pallidin) gene.

Nature genetics - 1 Sept 1992

White R A, Peters L L, Adkison L R, Korsgren C, Cohen C M, Lux S E

Abstract excerpt

Pallid is one of 12 independent murine mutations with a prolonged bleeding time that are models for human platelet storage pool deficiencies in which several intracellular organelles are abnormal. We have mapped the murine gene for protein 4.2 (Epb4.2) to chromosome 2 where it co-localizes with p...

Topics

Animals
Blood Proteins
Chromosome Mapping
Cytoskeletal Proteins
DNA
Disease Models, Animal
Gene Expression
Humans
Membrane Proteins
Mice
Mutation
Phenotype
Platelet Storage Pool Deficiency
RNA

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