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Chromosomal Alterations in Hepatocellular Nodules by Comparative Genomic Hybridization: High-Grade Dysplastic Nodules Represent Early Stages of Hepatocellular Carcinoma

1 May 2002

Abstract excerpt

Data from experimental hepatocarcinogenesis and recent studies in humans have suggested that the emergence of hepatocellular carcinoma (HCC) is a stepwise process. However, despite abundant experimental data, the precise molecular mechanisms and genetic alterations involved in human liver carcinogenesis are still unclear. Comparative genomic hybridization was used to analyze 26 hepatocellular nodules obtained...

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Chromosomal and Genetic Variations
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PMID: 12003995
DOI: 10.1038/labinvest.3780449

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