Article
Effects of apolipoprotein A-I genetic variations on plasma apolipoprotein, serum lipoprotein and glucose levels.
Clinical genetics - 1 Mar 2002
Larson I A, Ordovas J M, Barnard J R, Hoffmann M M, Feussner G, Lamon-Fava S, Schaefer E J
Abstract excerpt
The present authors investigated the individual and combined associations of the apolipoprotein (apo) A-I -75 bp and +83 bp polymorphisms with plasma lipid, lipoprotein and apolipoprotein levels in 734 Caucasian men and women. The frequency of the A allele at position -75 bp (G-->A) was 0.14 in women and 0.17 in men. The frequencies for the rare M2 allele at position +83 bp and/or 84 bp (C-->T and G-->A,...
Topics
- Apolipoprotein A-I
- Apolipoproteins
- Blood Glucose
- Cholesterol, HDL
- Cholesterol, LDL
- Female
- Gene Frequency
- Genotype
- Haplotypes
- Humans
- Male