Article
The search for type 2 diabetes susceptibility genes using whole-genome scans: an epidemiologist's perspective.
Diabetes/metabolism research and reviews - 1 Jan 2000
Stern Michael P
Abstract excerpt
Most whole-genome scan studies of type 2 diabetes have ascertained families on affected sibpairs. Although assuring enrollment of multiplex families, this strategy may lead to the enrollment of unrepresentative families, particularly in low-risk populations where relatively few diabetics have an affected sibling. In high-risk populations such as Hispanics and Native Americans, population-based ascertainment is...
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