Article
Increased generation of dendritic cells from myeloid progenitors in autoimmune-prone nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) - 15 May 2002
Steptoe Raymond J, Ritchie Janine M, Harrison Leonard C
Abstract excerpt
Aberrant dendritic cell (DC) development and function may contribute to autoimmune disease susceptibility. To address this hypothesis at the level of myeloid lineage-derived DC we compared the development of DC from bone marrow progenitors in vitro and DC populations in vivo in autoimmune diabetes-prone nonobese diabetic (NOD) mice, recombinant congenic nonobese diabetes-resistant (NOR) mice, and unrelated BALB/c...
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