Article
C-reactive protein levels are influenced by common IL-1 gene variations.
Cytokine - 21 Feb 2002
Berger Peter, McConnell Joseph P, Nunn Martha, Kornman Kenneth S, Sorrell Julian, Stephenson Katherine, Duff Gordon W
Abstract excerpt
Elevated markers of systemic inflammation are associated with the development of acute coronary syndromes, but there is no current explanation for increased inflammation in overtly healthy individuals. The influence of genetic control of the inflammatory response on the observed variability is unknown. We studied the frequency of four polymorphisms in interleukin (IL) 1 genes, known to modulate inflammation, in...
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