Article
Identification of an initiator-like element essential for the expression of the tissue inhibitor of metalloproteinases-4 (Timp-4) gene.
The Biochemical journal - 15 May 2002
Young David A, Phillips Blaine W, Lundy Caroline, Nuttall Robert K, Hogan Aileen, Schultz Gilbert A, Leco Kevin J, Clark Ian M, Edwards Dylan R
Abstract excerpt
We have used real-time quantitative reverse transcriptase PCR (TaqMan) to quantify the expression of the four tissue inhibitor of metalloproteinases (Timp) genes in mouse tissues during development and in the adult. Among the four Timp genes, Timp-4 shows the most restricted pattern of expression, with highest RNA levels in brain, heart and testes. These data indicate that in the brain, Timp-4 transcripts are...
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