Article
Production of testosterone from phytosterol using a single-step microbial transformation by a mutant of Mycobacterium sp.
Journal of industrial microbiology & biotechnology - 1 May 2002
Lo C-K, Pan C-P, Liu W-H
Abstract excerpt
A testosterone (TS)-producing mutant, ST2, was derived from a phytosterol-assimilating and androst-4-ene-3,17-dione (AD)-producing bacterium, Mycobacterium sp. B-3805S, using nitrosoguanidine (NTG) mutagenesis. Production of TS from phytosterol using a single-step microbial transformation process by ST2 was investigated in a 5-l surface-aeration microprocessor-controlled fermentor loaded with a synthetic medium...
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