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Article

Disentangling the MYC web

30 Apr 2002

Abstract excerpt

That MYC is causally associated with cancer has been apparent for decades. As a retroviral transforming gene or as the target of chromosomal translocations, rearrangements, amplification, mutations, and viral insertions, disturbance of MYC regulation and/or function is one of the most common molecular lesions contributing to multistep carcinogenesis (1–5). Disordered MYC expression alters cell proliferation, cell...

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Identifiers

PMID: 11983876
DOI: 10.1073/pnas.102173199

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