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Article

Expression of the Human Poliovirus Receptor/CD155 Gene Is Activated by Sonic Hedgehog

1 Jul 2002

Abstract excerpt

The human poliovirus receptor/CD155 is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The ectodomain of CD155 mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1. CD155 is a primate-restricted gene that is expressed during development in mesenchymal tissues and ventrally derived...

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PMID: 11983699
DOI: 10.1074/jbc.m201378200

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