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Article

Reliability of the comet assay in cryopreserved human sperm

1 May 2002

Abstract excerpt

BACKGROUND: Although the comet assay has potential value for measuring DNA damage in large epidemiological human sperm studies, it is impractical to perform the assay daily on fresh semen samples. Therefore, before its use in epidemiological studies, the reliability of the comet assay in measuring DNA damage in cryopreserved sperm should be compared with that in fresh human sperm. METHODS: Semen samples from 16...

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PMID: 11980751
DOI: 10.1093/humrep/17.5.1274

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