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Article

Characterization of Lentiviral Vector-Mediated Gene Transfer in Adult Mouse Brain

1 May 2002

Abstract excerpt

Lentiviral vectors are promising tools for gene transfer into the central nervous system. We have characterized in detail transduction with human immunodeficiency virus type 1 (HIV-1)-derived vectors encoding enhanced green fluorescent protein (eGFP) in the adult mouse brain. Different brain regions such as the striatum, hippocampus, and the lateral ventricle were targeted. The eGFP protein was transported...

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PMID: 11975850
DOI: 10.1089/10430340252899019

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