Article
Sertoli cell vacuolization and abnormal germ cell adhesion in mice deficient in an inositol polyphosphate 5-phosphatase.
Biology of reproduction - 1 May 2002
Hellsten Elina, Bernard David J, Owens Jennie W, Eckhaus Michael, Suchy Sharon F, Nussbaum Robert L
Abstract excerpt
The dynamic nature of cellular interactions during differentiation of germ cells and their translocation from the basement membrane to the lumen of the seminiferous tubules requires the existence of complex and well-regulated cellular adhesion mechanisms in the testis. Successful migration of the developing germ cells is characterized by dynamic breakage and reformation of cadherin-containing adherens junctions...
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