Article
[The use of the expectation-maximization (EM) algorithm for maximum likelihood estimation of gametic frequencies of multilocus polymorphic codominant systems based on sampled population data].
Genetika - 1 Mar 2002
Sergeev A S, Arapova R K
Abstract excerpt
Estimation of gametic frequencies in multilocus polymorphic systems based on the numerical distribution of multilocus genotypes in a population sample ("analysis without pedigrees") is difficult because some gametes are not recognized in the data obtained. Even in the case of codominant systems, where all alleles can be recognized by genotypes, so that direct estimation of the frequencies of genes (alleles) is...
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