Article
The brain insulin signal transduction system and sporadic (type II) Alzheimer disease: an update.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2002
Hoyer S
Abstract excerpt
Nosologically, Alzheimer disease may not be considered to be a single disorder in spite of a common clinical phenotype. Only a small proportion of about 5% to 10% of all Alzheimer cases is due to genetic mutations (type I) whereas the great majority of patients was found to be sporadic in origin. It may be assumed that susceptibility genes along with lifestyle risk factors contribute to the causation of the...
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