Article
Internalisation and retention of EGF-dextran associated radioactivity in transfected Chinese hamster ovary cells expressing the human EGF-receptor.
International journal of oncology - 1 May 2002
Olsson Pär, Collins V Peter, Liu Lu, Gedda Lars, Liljegren Asa, Carlsson Jörgen
Abstract excerpt
Chinese hamster ovary (CHO) cells transfected with the wild-type gene for the human epidermal growth factor-receptor (EGFR) and expressing the receptor in their cell membrane are, together with the receptor negative parent CHO cells, an interesting model system for experimental EGFR-targeting tumour therapy. Comparisons of effects on nearly identical cells with and without receptors can be made. The main purpose...
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