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Article

A negative-selection strategy for depleting myeloma cells from patients' BM and/or leukapheresis blood.

Cytotherapy - 1 Jan 2001

Louis S A, Zapf R, Clarke E, Thomas T E, Sutherland H J

Abstract excerpt

BACKGROUND: Autologous transplantation improves survival in multiple myeloma patients, however, most eventually relapse. As an attempt towards improving relapse-free survival, we designed a negative-selection purging strategy, to remove myeloma cells from leukapheresis harvests using MAbs specific for Ags on myeloma cells. METHODS: CD38 is highly expressed on myeloma plasma cells, but expressed at lower levels on...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11953033
DOI: 10.1080/146532401317248090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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