Article
Identification of candidate genes for Sjögren's syndrome using MRL/lpr mouse model of Sjögren's syndrome and cDNA microarray analysis.
Immunology letters - 1 May 2002
Azuma Takanori, Takei Masami, Yoshikawa Tsutomu, Nagasugi Yumi, Kato Masaki, Otsuka Motoyuki, Shiraiwa Hidetaka, Sugano Sumino, Mitamura Ko, Sawada Shigemasa, Masuho Yasuhiko, Seki Naohiko
Abstract excerpt
Sjögren's syndrome is a chronic autoimmune disease characterized by focal lymphocytic infiltration of lacrimal and salivary glands, but the precise mechanism of this syndrome is poorly understood. To clarify the mechanism of onset and progression of Sjögren's syndrome, it is necessary to identify Sjögren's syndrome-related genes. For this purpose, we used MLR/MpJ-lpr/lpr (MRL/lpr) mouse as a model of human...
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