Article
Determination of the relative contribution of three genes-the cystic fibrosis transmembrane conductance regulator gene, the cationic trypsinogen gene, and the pancreatic secretory trypsin inhibitor gene-to the etiology of idiopathic chronic pancreatitis.
European journal of human genetics : EJHG - 1 Feb 2002
Audrézet Marie-Pierre, Chen Jian-Min, Le Maréchal Cedric, Ruszniewski Philippe, Robaszkiewicz Michel, Raguénès Odile, Quéré Isabelle, Scotet Virginie, Férec Claude
Abstract excerpt
In the last 5 years, mutations in three genes, the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the cationic trypsinogen (PRSS1) gene, and the pancreatic secretory trypsin inhibitor (PSTI) gene, have been found to be associated with chronic pancreatitis (CP). In this study, using established mutation screening methods, we systematically analysed the entire coding sequences and all exon/intron...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.