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Article

Genetic control of neutrophil superoxide production in diabetes-resistant ALR/Lt mice.

Free radical biology & medicine - 15 Apr 2002

Mathews Clayton E, Dunn Brian D, Hannigan Michael O, Huang Chi-Kuang, Leiter Edward H

Abstract excerpt

The neutrophil oxidative burst reaction differentiates ALR/Lt mice, known for an unusual systemic elevation of antioxidant defenses, from ALS/Lt mice, a related strain known for reduced ability to withstand oxidative stress. Neutrophils from marrow of ALS mice produced a normal neutrophil oxidative burst following phorbol ester stimulation. In contrast, ALR mice exhibited a markedly suppressed superoxide burst....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11937300
DOI: 10.1016/s0891-5849(02)00747-5

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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