Genome wide oscillations in expression. Wavelet analysis of time series data from yeast expression arrays uncovers the dynamic architecture of phenotype.

Abstract excerpt

A reanalysis of expression arrays in yeast cells synchronized by alpha factor blockade or through the use of temperature sensitive mutants uncovered a genome wide pattern of oscillations in mRNA concentrations. Using wavelet decomposition as a signal processing technique and enhancement strategies borrowed from image processing, noise and trends in the Stanford yeast cell cycle data were partitioned away from...

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