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Article

Mutation screening of the human Clock gene in circadian rhythm sleep disorders.

Psychiatry research - 15 Mar 2002

Iwase Toshio, Kajimura Naofumi, Uchiyama Makoto, Ebisawa Takashi, Yoshimura Kimio, Kamei Yuichi, Shibui Kayo, Kim Keiko, Kudo Yoshinao, Katoh Masaaki, Watanabe Tsuyoshi, Nakajima Toru, Ozeki Yuji, Sugishita Mariko, Hori Toru, Ikeda Masaaki, Toyoshima Ryoichi, Inoue Yuichi, Yamada Naoto, Mishima Kazuo, Nomura Masahiko, Ozaki Norio, Okawa Masako, Takahashi Kiyohisa, Yamauchi Toshio

Abstract excerpt

We tested whether the human Clock (hClock) gene, one of the essential components of the circadian oscillator, is implicated in the vulnerability to delayed sleep phase syndrome (DSPS) and non-24-hour sleep-wake syndrome (N-24). Screening in the entire coding region of the hClock gene with PCR amp...

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PMID: 11927136
DOI: 10.1016/s0165-1781(02)00006-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11927136-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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