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Origin and Evolution of Influenza Virus Hemagglutinin Genes

1 Apr 2002

Abstract excerpt

Influenza A, B, and C viruses are the etiological agents of influenza. Hemagglutinin (HA) is the major envelope glycoprotein of influenza A and B viruses, and hemagglutinin-esterase (HE) in influenza C viruses is a protein homologous to HA. Because influenza A virus pandemics in humans appear to occur when new subtypes of HA genes are introduced from aquatic birds that are known to be the natural reservoir of the...

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PMID: 11919291
DOI: 10.1093/oxfordjournals.molbev.a004105

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