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Avian Influenza Virus Exhibits Rapid Evolutionary Dynamics

31 Aug 2006

Abstract excerpt

Influenza A viruses from wild aquatic birds, their natural reservoir species, are thought to have reached a form of stasis, characterized by low rates of evolutionary change. We tested this hypothesis by estimating rates of nucleotide substitution in a diverse array of avian influenza viruses (AIV) and allowing for rate variation among lineages. The rates observed were extremely high, at >10(-3) substitutions per...

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PMID: 16945980
DOI: 10.1093/molbev/msl102

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